Structural and synaptic plasticity in stress-related disorders

Regulates Structural Synaptic Plasticity

Plasticity and mTOR: Towards Restoration of Impaired Synaptic Plasticity in mTOR-Related Neurogenetic Disorders

OBJECTIVE To review the recent literature on the clinical features, genetic mutations, neurobiology associated with dysregulation of mTOR (mammalian target of rapamycin), and clinical trials for tuberous sclerosis complex (TSC), neurofibromatosis-1 (NF1) and fragile X syndrome (FXS), and phosphatase and tensin homolog hamartoma syndromes (PTHS), which are neurogenetic disorders associated with ...

P7: The Role of Aquaporins in Synaptic Plasticity and Epilepsy

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Geometry and Structural Plasticity of Synaptic Connectivity

Changes in synaptic connectivity patterns through the formation and elimination of dendritic spines may contribute to structural plasticity in the brain. We characterize this contribution quantitatively by estimating the number of different synaptic connectivity patterns attainable without major arbor remodeling. This number depends on the ratio of the synapses on a dendrite to the axons that p...

Memory Capacities for Synaptic and Structural Plasticity

Neural associative networks with plastic synapses have been proposed as computational models of brain functions and also for applications such as pattern recognition and information retrieval. To guide biological models and optimize technical applications, several definitions of memory capacity have been used to measure the efficiency of associative memory. Here we explain why the currently use...